Seroepidemiology of Middle East respiratory syndrome (MERS) coronavirus in Saudi Arabia (1993) and Australia (2014) and characterisation of assay specificity.

نویسندگان

  • M G Hemida
  • R A Perera
  • R A Al Jassim
  • G Kayali
  • L Y Siu
  • P Wang
  • K W Chu
  • S Perlman
  • M A Ali
  • A Alnaeem
  • Y Guan
  • L L Poon
  • L Saif
  • M Peiris
چکیده

The pseudoparticle virus neutralisation test (ppNT) and a conventional microneutralisation (MN) assay are specific for detecting antibodies to Middle East respiratory syndrome coronavirus (MERS-CoV) when used in seroepidemiological studies in animals. Genetically diverse MERS-CoV appear antigenically similar in MN tests. We confirm that MERS-CoV was circulating in dromedaries in Saudi Arabia in 1993. Preliminary data suggest that feral Australian dromedaries may be free of MERS-CoV but larger confirmatory studies are needed.

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عنوان ژورنال:
  • Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

دوره 19 23  شماره 

صفحات  -

تاریخ انتشار 2014